In pharmaceutical analysis, there can be seen a great application of capillary columns. There are numerous ingredients and products for which these columns can be used. Capillary gas chromatography is the most selective technique that is used for the analysis of essential oils. This sort of column is considered as the chromatographic way for the separation and analysis of any chemical warfare agent.
What Capillary GC columns are? GC columns are extensively used to analyze samples for any individual chemical compounds. There’s a huge demand for this GC column that is used in the petroleum and pharmaceutical industries. The main objective of using these columns is to test for impurities in the chemical agents. In clinical laboratories, capillary columns are used to determine the chemical makeup of a particular sample. When it comes to efficiency, a capillary CG column is considered a more efficient way of separating the sample than a packed column. A packed column is also a type that is used for pharmaceutical analysis. There are some differences between these types of capillary GC columns including size and whether and end cap. One main difference between these columns is the stationary phase itself and how polar it is. How to choose the capillary columns? Here are some factors depending on which you can select the columns. Let’s have a look at some of the factors in a detailed manner- Sample size One of the factors on which the selection depends is the size of the sample that needs to be analyzed. These days, all detectors come with high sensitivities thus there will be no need for large sample injections. In such situations, the most preferred choice is the capillary columns. In case if detector sensitivity is low then such situation packed columns can be considered. This sort of columns is used as these have higher sample load capacities. Stationary phase options Another factor on which the selection of GC column is dependent is the stationery phase option. There’s the availability of fewer stationary phase options for capillary columns than for packed columns. This can be regarded as both plus and minus points. Fixed gas analysis In different industries such as petrochemical and environmental science, packed columns are mainly used for the analysis of fixed gases. This can help in achieving a better separation of these gases than capillary columns. Cost of the columns In general, capillary columns are a bit expensive because of their features. The packed columns are considered less expensive than capillary columns which are always important for balancing your analytical needs with your budget. Make sure to connect with the reliable GC Column Manufacturers that offer the best and high performance GC columns.
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